Programme (preliminary)

 

X-linked Adrenoleukodystrophy: Past Achievements and Future Partnerships
Friday, 08.05.26, 08:30 am

 

Welcome and Introduction

Joseph Claßen, Leipzig

 

Session 1: Histopathologic Features and Biological Foundations

Chairs: Ruth Stassart, Leipzig & Florian Eichler, Boston

 

X-ALD Histopathology in the Context of White Matter Disorders

Christine Stadelmann, Göttingen

Insights from Cellular Phenotyping in X-ALD

Caroline Bergner, Leipzig

Organelle Pathology in X-ALD

Aurora Pujol, Barcelona

Biomarkers for Diagnosis and Monitoring of Disease Progression

Isabelle Weinhofer, Vienna

 

Session 2: Clinical Monitoring – Towards International Collaboration

Chairs: Ludger Schöls, Tübingen & Ettore Salsano, Milano

 

European Collaborative Networks in Rare Diseases

Ludger Schöls, Tübingen

Federated Registries and International Databases for Adult  Cerebral ALD

Julia Lier, Leipzig & Eda Kabak, Amsterdam

Clinical Monitoring of Disease Progression in Adrenomyeloneuropathy

Marc Engelen, Amsterdam

Neuropsychological Assessment in Adult Leukodystrophy Patients

Lisa Schäfer, Leipzig

Natural History of Cerebral Lesions in Adult X-ALD

Markus Ponleitner, Vienna

 

Session 3: X-ALD Therapy

Chairs: Ali Fatemi, Baltimore & Johannes Berger, Vienna

 

Emerging and Future Therapeutic Strategies in Leukodystrophies

Ali Fatemi, Baltimore

Lerigltazone - A New Treatment Option in ALD?

Fanny Mochel, Paris

HSCT and Gene Therapy in Childhood Cerebral ALD

Troy Lund, Minneapolis

Long-term Outcomes in Transplanted Childhood Cerebral ALD

Jörn Kühl, Leipzig

Allogeneic HSCT in Adulthood Cerebral ALD

Georg Franke, Leipzig

Targeting Cancer Cells with Chimeric Antigen Receptors (CARs) – a “Blueprint” and Potential New Strategy in Treating Leukodystrophies?

Ulrike Köhl, Leipzig

 

Session 4: A Century of X-ALD Research: From Discovery to Future Perspectives

Chairs: Ann Moser & Wolfgang Köhler

 

100 years X-linked Adrenoleukodystrophy

Florian Eichler, Boston

Hope and Challenges - The Patient Perspective

Martin Büchler, ELA Deutschland

Past and Future: the German X-ALD Story and Closing Remarks

Wolfgang Köhler, Leipzig