Programme (preliminary)

 

Certification: 30 CPD points

 

X-linked Adrenoleukodystrophy: Past Achievements and Future Partnerships
Friday, 08.05.26, 08:30 am

 

Welcome and Introduction

​ Joseph Claßen, Leipzig 

 

Session 1: Histopathologic Features and Biological Foundations

Chairs:

​Ruth Stassart, Leipzig &
Florian Eichler, Boston

 

​X-ALD Histopathology in the Context of White Matter DisordersChristine Stadelmann, Göttingen

​Insights from Cellular Phenotyping in X-ALDCaroline Bergner, Leipzig

​Organelle Pathology in X-ALDAurora Pujol, Barcelona

​Biomarkers for Diagnosis and Monitoring of Disease ProgressionIsabelle Weinhofer, Vienna

 

Session 2: Clinical Monitoring – Towards International Collaboration

Chairs:

​Ludger Schöls, Tübingen & Ettore Salsano, Milano

 

​European Collaborative Networks in Rare DiseasesLudger Schöls, Tübingen

​Federated Registries and International Databases for Adult  Cerebral ALDJulia Lier, Leipzig & Eda Kabak, Amsterdam

 

​Clinical Monitoring of Disease Progression in AdrenomyeloneuropathyMarc Engelen, Amsterdam

​Neuropsychological Assessment in Adult Leukodystrophy PatientsLisa Schäfer, Leipzig

​Natural History of Cerebral Lesions in Adult X-ALDMarkus Ponleitner, Vienna

 

Session 3: X-ALD Therapy

Chairs:

​Ali Fatemi, Baltimore & Johannes Berger, Vienna

 

​Emerging and Future Therapeutic Strategies in LeukodystrophiesAli Fatemi, Baltimore

​Lerigltazone - A New Treatment Option in ALD?Fanny Mochel, Paris

​HSCT and Gene Therapy in Childhood Cerebral ALDTroy Lund, Minneapolis

​Long-term Outcomes in Transplanted Childhood Cerebral ALDJörn Kühl, Leipzig

​Allogeneic HSCT in Adulthood Cerebral ALDGeorg Franke, Leipzig

​Targeting Cancer Cells with Chimeric Antigen Receptors (CARs) – a “Blueprint” and Potential New Strategy in Treating Leukodystrophies?Ulrike Köhl, Leipzig

 

Session 4: A Century of X-ALD Research: From Discovery to Future Perspectives

Chairs:

​Ann Moser & Wolfgang Köhler

 

​100 years X-linked AdrenoleukodystrophyFlorian Eichler, Boston

​Hope and Challenges - The Patient PerspectiveMartin Büchler, ELA Deutschland

​Past and Future: the German X-ALD Story and Closing RemarksWolfgang Köhler, Leipzig